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Biology is spatial

At Spatial Genomics, we are dedicated to empowering discovery. We believe that our highly multiplexed spatial analysis will advance fundamental biology, precision medicine, drug development, and diagnostics.

Spatial Genomics reveals biology. We can simultaneously assay single-cell gene expression, protein expression, and genomic and epigenomic states within intact cells and tissues. As a result, we catalog more than cell states: we can also assess cell neighborhoods, interactions, and influences.

Decoding molecular identities

We have developed sequential fluorescence in situ hybridization (seqFISH), an advanced biomolecular analysis method that merges imaging with combinatorial molecular barcoding. Our single unifying platform reveals previously unexplored biology through super-resolution subcellular imaging of RNA, DNA, and protein. We can generate multi-omic analyses beyond the capabilities of other types of spatial analyses, with the flexibility to assess the expression of as many genes as required.

Technology

Resolving single cells

Cells are a fundamental unit of life. Our technology enables a more comprehensive picture of biology at a single-cell level. We are improving the understanding of cell biology by adding to the known diversity of cellular types and states, identifying the locations of transcripts and proteins at a subcellular level, and exploring the epigenetic and genomic bases for cell fate and function.

Applications

Tissue is the last frontier

Tissues and organs are composed of complex mixtures of cell types. Spatial Genomics analyzes highly multiplexed biomolecular identities and locations within single cells, through high-resolution imaging of intact tissue samples. With this more highly resolved view of cells within tissue microenvironments, we will better understand fundamental biology, health, and disease.